Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0028PFAM: protein of unknown function UPF0153; KEGG: met:M446_0025 hypothetical protein. (100 aa)    
Predicted Functional Partners:
Mnod_0029
KEGG: met:M446_0026 putative signal peptide.
       0.786
Mnod_0030
PFAM: thioesterase superfamily protein; KEGG: met:M446_0027 thioesterase superfamily protein.
       0.684
Mnod_6180
KEGG: rpe:RPE_2953 hypothetical protein.
  
     0.678
Mnod_6063
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
  
   0.657
Mnod_0027
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.457
Mnod_6772
PFAM: GYD family protein; KEGG: met:M446_6926 GYD family protein.
  
     0.422
Mnod_1306
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: met:M446_0938 integral membrane sensor signal transduction histidine kinase.
  
     0.407
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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