Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0039TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: met:M446_0037 crotonyl-CoA reductase. (431 aa)    
Predicted Functional Partners:
Mnod_5970
PFAM: MaoC domain protein dehydratase; KEGG: met:M446_5194 dehydratase.
 
 0.952
Mnod_4142
TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: met:M446_4406 methylmalonyl-CoA epimerase.
  
  0.906
Mnod_0038
TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; KEGG: met:M446_0036 methylmalonyl-CoA mutase, large subunit.
 
   
 0.855
Mnod_3627
PFAM: MaoC domain protein dehydratase; KEGG: met:M446_3940 dehydratase.
 
 
 0.827
Mnod_4511
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: met:M446_4575 isovaleryl-CoA dehydrogenase.
 
   0.770
Mnod_7178
PFAM: HpcH/HpaI aldolase; KEGG: met:M446_6315 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.764
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
  
 
 0.753
Mnod_7119
PFAM: HpcH/HpaI aldolase; KEGG: met:M446_6559 citrate (pro-3S)-lyase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.491
Mnod_5949
PFAM: HpcH/HpaI aldolase; KEGG: met:M446_5220 citryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.412
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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