STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0049PFAM: AMP-dependent synthetase and ligase; KEGG: mex:Mext_2140 AMP-dependent synthetase and ligase. (510 aa)    
Predicted Functional Partners:
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
  
 0.954
Mnod_4838
TIGRFAM: oxalyl-CoA decarboxylase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: met:M446_4056 oxalyl-CoA decarboxylase; Belongs to the TPP enzyme family.
 
 
 
  0.927
frc
formyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.
    
 0.901
frc-2
formyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.
    
 0.901
Mnod_0050
TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: mpo:Mpop_2099 2-dehydropantoate 2-reductase.
 
     0.823
Mnod_5227
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: met:M446_3267 respiratory-chain NADH dehydrogenase domain-containing protein.
    
 
 0.680
Mnod_6726
PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_6525 AMP-dependent synthetase and ligase.
  
     0.578
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.507
Mnod_0052
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: met:M446_0052 glutamine amidotransferase of anthranilate synthase.
   
   0.487
Mnod_0051
PFAM: aminotransferase class IV; KEGG: met:M446_0051 aminotransferase class IV.
  
    0.467
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.