Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0059PFAM: extracellular solute-binding protein family 1; KEGG: met:M446_0059 extracellular solute-binding protein. (370 aa)    
Predicted Functional Partners:
Mnod_0058
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: met:M446_0058 integral membrane sensor signal transduction histidine kinase.
     0.985
Mnod_6368
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: met:M446_5860 binding-protein-dependent transport systems inner membrane component.
  
 
 0.948
Mnod_2764
PFAM: extracellular solute-binding protein family 1; KEGG: met:M446_6139 extracellular solute-binding protein.
  
  
 
0.918
Mnod_5871
PFAM: extracellular solute-binding protein family 1; KEGG: bbr:BB1902 putative periplasmic protein.
     
 0.903
Mnod_6369
PFAM: extracellular solute-binding protein family 1; KEGG: met:M446_5861 extracellular solute-binding protein.
     
 0.903
Mnod_0057
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: met:M446_0057 two component transcriptional regulator.
 
     0.860
Mnod_6370
PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: met:M446_5862 ABC transporter related; Belongs to the ABC transporter superfamily.
  
 
 0.840
Mnod_0056
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: met:M446_0056 ABC transporter related.
       0.573
Mnod_0061
KEGG: met:M446_2473 hypothetical protein.
 
     0.573
Mnod_2766
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: met:M446_6141 integral membrane sensor signal transduction histidine kinase.
     0.534
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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