Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0078PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:pRL120502 putative guanylate/adenylate cyclase. (471 aa)    
Predicted Functional Partners:
Mnod_2387
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; KEGG: met:M446_6425 adenylate/guanylate cyclase with integral membrane sensor.
  
     0.725
Mnod_3196
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sil:SPO0751 adenylate/guanylate cyclase.
  
     0.712
Mnod_0315
PFAM: ferredoxin; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: met:M446_2293 adenylate/guanylate cyclase.
  
     0.711
Mnod_5259
KEGG: mrd:Mrad2831_1495 adenylate/guanylate cyclase.
  
     0.694
Mnod_0096
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: met:M446_0534 adenylate/guanylate cyclase.
  
 
 
 0.692
Mnod_4597
Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: met:M446_0722 adenylate/guanylate cyclase with CHASE sensor.
 
   
 0.675
Mnod_3461
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMa1103 adenylate/guanylate cyclase.
  
     0.662
Mnod_0812
KEGG: met:M446_3613 putative adenylate/guanylate cyclase.
  
     0.626
Mnod_7320
PFAM: cyclic nucleotide-binding; KEGG: met:M446_4039 cyclic nucleotide-binding protein.
 
   0.578
Mnod_4159
KEGG: met:M446_4423 putative adenylate/guanylate cyclase.
  
     0.542
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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