Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0114KEGG: met:M446_4750 hypothetical protein. (311 aa)    
Predicted Functional Partners:
Mnod_6741
PFAM: heat shock protein DnaJ domain protein; KEGG: met:M446_6495 heat shock protein DnaJ domain-containing protein.
  
     0.668
Mnod_0115
PFAM: FAD dependent oxidoreductase; KEGG: met:M446_4751 sarcosine oxidase.
       0.608
Mnod_7422
PFAM: GcrA cell cycle regulator; KEGG: met:M446_6684 GcrA cell cycle regulator.
  
     0.580
Mnod_2892
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
     0.576
prmC
Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.558
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.557
Mnod_1608
TIGRFAM: double-strand break repair protein AddB; KEGG: met:M446_0491 double-strand break repair protein AddB.
  
     0.523
Mnod_1610
TIGRFAM: double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; KEGG: met:M446_0489 double-strand break repair helicase AddA; Belongs to the helicase family. UvrD subfamily.
  
     0.514
Mnod_4617
PFAM: protein of unknown function DUF448; KEGG: met:M446_2612 hypothetical protein.
  
     0.507
Mnod_5219
PFAM: protein of unknown function DUF1674; KEGG: met:M446_2962 hypothetical protein.
  
     0.468
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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