Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0145PFAM: CoA-binding domain protein; KEGG: met:M446_4615 CoA-binding domain-containing protein. (181 aa)    
Predicted Functional Partners:
Mnod_4793
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: met:M446_2635 O-acetylhomoserine/O-acetylserine sulfhydrylase.
      0.756
Mnod_4812
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: met:M446_2633 O-acetylhomoserine/O-acetylserine sulfhydrylase.
      0.681
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: met:M446_2230 ferric uptake regulator family protein; Belongs to the Fur family.
  
    0.628
Mnod_5586
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: met:M446_5385 ferric uptake regulator family protein; Belongs to the Fur family.
  
    0.628
Mnod_5738
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: rpc:RPC_3503 ferric uptake regulator, FUR family; Belongs to the Fur family.
  
    0.628
Mnod_3337
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: met:M446_4319 O-acetylhomoserine/O-acetylserine sulfhydrylase.
      0.569
Mnod_4713
PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: met:M446_4198 flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
    
   0.559
Mnod_0146
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: met:M446_4614 enoyl-CoA hydratase/isomerase.
       0.552
Mnod_0147
PFAM: thioesterase superfamily protein; KEGG: met:M446_4613 thioesterase superfamily protein.
       0.545
Mnod_2668
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mex:Mext_3330 O-acetylhomoserine/O-acetylserine sulfhydrylase.
      0.536
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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