Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0170TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; KEGG: met:M446_4589 nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (287 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 
 0.999
Mnod_0169
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: met:M446_4590 L-aspartate oxidase.
  
 0.999
pncB
Nicotinate phosphoribosyltransferase-like protein; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
   
 0.981
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.943
Mnod_0167
KEGG: met:M446_4592 hypothetical protein.
 
    0.930
Mnod_6535
PFAM: CinA domain protein; KEGG: met:M446_5926 CinA domain-containing protein; Belongs to the CinA family.
     
 0.919
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.907
Mnod_6550
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: met:M446_5947 MazG family protein.
    
  0.906
Mnod_4645
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: met:M446_2582 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family.
    
  0.901
Mnod_1047
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: met:M446_1666 NUDIX hydrolase.
     
 0.900
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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