Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (732 aa)    
Predicted Functional Partners:
Mnod_0409
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: met:M446_6099 phosphate butyryltransferase.
  
 
 0.980
Mnod_2174
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_2472 malate dehydrogenase.
  
 
 0.978
Mnod_2328
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_1243 malate dehydrogenase.
  
 
 0.978
Mnod_7102
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_6546 malate dehydrogenase.
  
 
 0.978
Mnod_1524
TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: met:M446_0646 citrate synthase I; Belongs to the citrate synthase family.
   
 0.973
Mnod_6908
PFAM: phosphate acetyl/butaryl transferase; KEGG: met:M446_1569 phosphate butyryltransferase.
  
 
 0.962
Mnod_0680
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: met:M446_1761 hypothetical protein.
  
 
 0.951
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.950
Mnod_1158
PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_2199 AMP-dependent synthetase and ligase.
   
 0.933
Mnod_3983
PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro06598 acetate--CoA ligase.
   
 0.933
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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