Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Mnod_0229PFAM: protein of unknown function DUF849; KEGG: met:M446_3176 hypothetical protein. (293 aa)    
Predicted Functional Partners:
Mnod_0228
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: met:M446_3175 short-chain dehydrogenase/reductase SDR.
 
    0.870
Mnod_5148
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: met:M446_4506 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
 
  
 0.725
Mnod_6457
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: bxe:Bxe_C0922 putative 3-hydroxyacyl-CoA dehydrogenase.
 
  
 0.708
Mnod_0517
KEGG: met:M446_2034 hypothetical protein.
 
  
 0.625
Mnod_5261
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: met:M446_3297 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
 
  
 0.591
Mnod_5118
KEGG: met:M446_3024 hypothetical protein.
  
  
 0.539
Mnod_2278
TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase; KEGG: met:M446_1572 3-oxoacid CoA-transferase, B subunit.
    
 0.532
Mnod_6918
PFAM: Cupin 2 conserved barrel domain protein; KEGG: met:M446_6465 cupin 2 domain-containing protein.
  
    0.520
Mnod_0227
PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: met:M446_3170 IclR family transcriptional regulator.
  
    0.507
Mnod_3695
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: met:M446_4642 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
 
  
 0.459
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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