STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0263Protein CoxF; KEGG: met:M446_2346 protein CoxF. (50 aa)    
Predicted Functional Partners:
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
       0.853
ctaG
Cytochrome c oxidase assembly protein CtaG/Cox11; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.
       0.829
Mnod_0393
KEGG: met:M446_2218 hypothetical protein.
  
     0.667
Mnod_7241
KEGG: met:M446_6043 outer membrane lipoprotein omp19.
  
     0.642
Mnod_0261
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
       0.638
Mnod_7575
PFAM: RDD domain containing protein; KEGG: met:M446_6837 RDD domain-containing protein.
  
     0.626
Mnod_4517
KEGG: met:M446_3666 hypothetical protein.
  
     0.622
Mnod_7582
KEGG: met:M446_6846 hypothetical protein.
  
     0.622
Mnod_4444
KEGG: met:M446_3249 hypothetical protein.
  
     0.620
Mnod_0265
PFAM: cytochrome c oxidase subunit III; KEGG: met:M446_2344 cytochrome c oxidase subunit III.
       0.605
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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