Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0276KEGG: met:M446_2334 beta-lactamase domain-containing protein. (308 aa)    
Predicted Functional Partners:
Mnod_0275
KEGG: met:M446_2335 ABC-type multidrug transport system ATPase and permease components-like protein.
 
     0.778
Mnod_5259
KEGG: mrd:Mrad2831_1495 adenylate/guanylate cyclase.
 
     0.719
Mnod_7519
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: met:M446_6772 adenylate/guanylate cyclase.
 
     0.719
Mnod_3196
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sil:SPO0751 adenylate/guanylate cyclase.
 
     0.702
Mnod_4405
PFAM: cyclic nucleotide-binding; KEGG: met:M446_2719 cyclic nucleotide-binding protein.
 
     0.684
Mnod_0315
PFAM: ferredoxin; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: met:M446_2293 adenylate/guanylate cyclase.
 
     0.674
Mnod_3461
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMa1103 adenylate/guanylate cyclase.
 
     0.669
Mnod_0163
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rle:pRL110185 putative transmembrane adenylate cyclase.
 
     0.653
Mnod_4597
Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: met:M446_0722 adenylate/guanylate cyclase with CHASE sensor.
 
     0.649
Mnod_4159
KEGG: met:M446_4423 putative adenylate/guanylate cyclase.
 
     0.577
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: medium (48%) [HD]