Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Mnod_0291PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: met:M446_2316 carbamoyl-phosphate synthase L chain ATP-binding. (649 aa)    
Predicted Functional Partners:
Mnod_0290
PFAM: carboxyl transferase; KEGG: met:M446_2317 propionyl-CoA carboxylase.
 0.997
Mnod_0289
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: met:M446_2318 acyl-CoA dehydrogenase domain-containing protein.
  
 0.964
Mnod_5510
PFAM: carboxyl transferase; KEGG: met:M446_3811 carboxyl transferase.
 
 0.943
Mnod_5242
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: met:M446_3281 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
 0.941
Mnod_0900
TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: rso:RS05395 hypothetical protein.
 
 
 0.935
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 
 0.935
Mnod_0153
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: met:M446_4606 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.928
Mnod_1203
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: jan:Jann_1327 acyl-CoA dehydrogenase-like.
  
 0.921
Mnod_4413
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: met:M446_3408 acyl-CoA dehydrogenase domain-containing protein.
  
 0.921
Mnod_4418
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: met:M446_3403 acyl-CoA dehydrogenase type 2.
  
 0.921
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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