Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0310PFAM: ROK family protein; KEGG: met:M446_2296 ROK family protein. (307 aa)    
Predicted Functional Partners:
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.962
Mnod_0875
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; KEGG: met:M446_5186 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
    
 0.930
Mnod_5608
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; KEGG: rpe:RPE_3497 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
    
 0.930
Mnod_6330
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; KEGG: met:M446_5186 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
    
 0.930
Mnod_1601
PFAM: sugar isomerase (SIS); KEGG: met:M446_0495 glutamine--fructose-6-phosphate transaminase (isomerizing).
    
  0.927
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.924
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.923
Mnod_3263
TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: met:M446_2697 fructose-1,6-bisphosphatase, class II.
   
 
 0.916
Mnod_5268
PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: met:M446_3077 alpha amylase catalytic region.
    
 0.911
fbp
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: met:M446_2282 inositol phosphatase/fructose-16-bisphosphatase; Belongs to the FBPase class 1 family.
     
  0.900
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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