STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Mnod_0366Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (377 aa)    
Predicted Functional Partners:
Mnod_4485
TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: met:M446_4553 gamma-glutamyltransferase.
 
 
 0.930
gshB
TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; KEGG: met:M446_1113 glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
    
 0.920
Mnod_3710
PFAM: gamma-glutamyltranspeptidase; KEGG: met:M446_2556 gamma-glutamyltransferase.
  
 
 0.918
Mnod_7293
Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
    
  0.903
Mnod_0899
PFAM: Allophanate hydrolase subunit 1; KEGG: bcm:Bcenmc03_3056 allophanate hydrolase subunit 1.
     
  0.900
Mnod_0900
TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: rso:RS05395 hypothetical protein.
     
  0.900
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
pxpA-2
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
Mnod_1105
TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: met:M446_2133 UreA amidolyase related protein.
     
  0.900
Mnod_5475
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: met:M446_0267 aminopeptidase N.
     
 0.900
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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