Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0416KEGG: met:M446_2087 hypothetical protein. (353 aa)    
Predicted Functional Partners:
Mnod_0417
KEGG: met:M446_2086 hypothetical protein.
 
   
 0.966
Mnod_0418
PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: met:M446_2085 glucose-methanol-choline oxidoreductase.
 
   
 0.945
Mnod_0415
PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: met:M446_2088 mandelate racemase/muconate lactonizing protein.
 
     0.915
Mnod_0414
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: met:M446_2089 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family.
 
   
 0.913
Mnod_0420
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: met:M446_2083 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.858
Mnod_0419
PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: met:M446_2084 SMP-30/gluconolaconase/LRE domain-containing protein.
       0.742
Mnod_0413
Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: met:M446_5720 Crp/FNR family transcriptional regulator.
       0.444
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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