Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Mnod_0451PFAM: 2OG-Fe(II) oxygenase; KEGG: met:M446_2016 2OG-Fe(II) oxygenase. (215 aa)    
Predicted Functional Partners:
Mnod_0501
Transcriptional regulator, AraC family; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: met:M446_1042 AraC family transcriptional regulator.
 
  
 0.783
Mnod_0452
KEGG: met:M446_2015 hypothetical protein.
       0.740
Mnod_0050
TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: mpo:Mpop_2099 2-dehydropantoate 2-reductase.
   
    0.628
Mnod_1448
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.628
Mnod_3347
KEGG: mrd:Mrad2831_4659 hypothetical protein.
   
    0.628
Mnod_6687
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.628
Mnod_0122
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: met:M446_4755 4-hydroxyphenylpyruvate dioxygenase.
  
    0.590
Mnod_0450
PFAM: protein of unknown function DUF6 transmembrane; KEGG: met:M446_2060 hypothetical protein.
       0.551
Mnod_1846
PFAM: HhH-GPD family protein; KEGG: met:M446_4878 HhH-GPD family protein.
     
 0.507
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
       0.470
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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