Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
Mnod_0536PFAM: aldo/keto reductase; KEGG: mex:Mext_4689 aldo/keto reductase. (291 aa)    
Predicted Functional Partners:
Mnod_1059
TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: met:M446_1429 pyridoxal kinase; Belongs to the pyridoxine kinase family.
  
 
 0.906
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
     
 0.904
Mnod_6439
PFAM: aldo/keto reductase; KEGG: bja:bll6256 dehydrogenase.
 
 
 0.502
Mnod_3345
PFAM: aldo/keto reductase; KEGG: xac:XAC1212 oxidoreductase.
 
 
0.481
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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