Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0632PFAM: cell divisionFtsK/SpoIIIE; KEGG: mpt:Mpe_B0175 DNA segregation ATPase FtsK/SpoIIIE-related protein. (1679 aa)    
Predicted Functional Partners:
Mnod_0636
KEGG: cyt:cce_5237 hypothetical protein.
 
     0.864
Mnod_0641
Hypothetical protein; KEGG: mpt:Mpe_B0172 putative ATP-binding protein.
 
    0.717
Mnod_0637
PFAM: phosphoadenosine phosphosulfate reductase; KEGG: cyt:cce_5239 hypothetical protein.
 
     0.676
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
   
 
 0.622
Mnod_0642
KEGG: cyt:cce_5254 hypothetical protein.
 
     0.618
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.613
Mnod_0633
Hypothetical protein; KEGG: met:M446_5531 transposase.
 
     0.612
Mnod_1025
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: met:M446_1407 ParB-like partition protein; Belongs to the ParB family.
  
  
 0.598
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
  
 0.494
Mnod_1532
KEGG: met:M446_0637 membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein.
 
  
 0.487
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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