Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_0698PFAM: Abortive infection protein; KEGG: met:M446_1092 abortive infection protein. (244 aa)    
Predicted Functional Partners:
Mnod_4676
PFAM: protein of unknown function DUF181; KEGG: met:M446_3967 hypothetical protein.
  
  
 0.830
Mnod_4359
KEGG: mrd:Mrad2831_5355 hypothetical protein.
  
  
 0.777
Mnod_4360
KEGG: mex:Mext_4583 polysaccharide biosynthesis protein.
  
    0.763
Mnod_5195
KEGG: met:M446_4457 hypothetical protein.
  
     0.753
Mnod_1883
PFAM: protein of unknown function DUF1624; KEGG: met:M446_0380 hypothetical protein.
 
    0.744
Mnod_5605
SMART: Parallel beta-helix repeat; KEGG: mpo:Mpop_4608 hemolysin-type calcium-binding region.
  
     0.720
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.714
Mnod_0307
KEGG: met:M446_2298 hypothetical protein.
 
     0.709
Mnod_0156
KEGG: met:M446_4603 hypothetical protein.
  
    0.697
Mnod_6551
PFAM: plasmid encoded RepA protein; KEGG: met:M446_5948 plasmid encoded RepA protein.
  
     0.696
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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