STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0701HflK protein; HflC and HflK could encode or regulate a protease. (389 aa)    
Predicted Functional Partners:
Mnod_0702
HflC protein; HflC and HflK could regulate a protease.
 
 
 0.998
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.969
hflX
GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.868
Mnod_2347
TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: met:M446_2991 cytochrome c oxidase, subunit II.
   
 
 0.803
Mnod_6886
TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: met:M446_5817 cytochrome c oxidase, subunit II.
   
 
 0.769
yidC
YidC translocase/secretase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.754
Mnod_0703
KEGG: met:M446_1087 hypothetical protein.
     
 0.737
Mnod_0704
TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: met:M446_1086 protease Do; Belongs to the peptidase S1C family.
 
 
 0.640
Mnod_0700
Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.601
Mnod_6549
PFAM: protein of unknown function DUF107; KEGG: xau:Xaut_1881 hypothetical protein.
 
 
 0.566
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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