Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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gshBTIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; KEGG: met:M446_1113 glutathione synthetase; Belongs to the prokaryotic GSH synthase family. (318 aa)    
Predicted Functional Partners:
Mnod_4666
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
  
  
 0.952
pepA
Peptidase M17 leucyl aminopeptidase domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.950
Mnod_5366
PFAM: Glutathione S-transferase domain; KEGG: met:M446_5058 glutathione S-transferase domain-containing protein.
 
  
 0.949
Mnod_7293
Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
    
 0.945
Mnod_2859
PFAM: Glutathione S-transferase domain; KEGG: met:M446_3771 glutathione S-transferase domain-containing protein; Belongs to the GST superfamily.
 
  
 0.941
Mnod_6782
PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: met:M446_6389 leucyl aminopeptidase; Belongs to the peptidase M17 family.
   
 
 0.931
Mnod_5423
PFAM: Glutathione S-transferase domain; KEGG: met:M446_0214 glutathione S-transferase domain-containing protein.
 
  
 0.930
Mnod_6935
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
  
  
 0.930
Mnod_1699
PFAM: Glutathione S-transferase domain; KEGG: met:M446_4826 glutathione S-transferase domain-containing protein.
 
  
 0.929
Mnod_4485
TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: met:M446_4553 gamma-glutamyltransferase.
 
  
 0.927
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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