STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0746PFAM: Aldehyde Dehydrogenase; KEGG: met:M446_1176 aldehyde dehydrogenase. (477 aa)    
Predicted Functional Partners:
Mnod_0063
PFAM: iron-containing alcohol dehydrogenase; KEGG: met:M446_3465 iron-containing alcohol dehydrogenase.
  
 0.926
Mnod_1844
PFAM: HpcH/HpaI aldolase; KEGG: met:M446_4880 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.908
Mnod_7095
PFAM: HpcH/HpaI aldolase; KEGG: met:M446_6205 2-dehydro-3-deoxyglucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.908
Mnod_5513
PFAM: aminotransferase class-III; KEGG: met:M446_3814 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.904
Mnod_1263
PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: met:M446_1642 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.
    
  0.901
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.883
Mnod_1126
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region; KEGG: met:M446_2164 2-oxoglutarate dehydrogenase, E1 subunit.
   
 0.879
Mnod_1524
TIGRFAM: citrate synthase I; PFAM: Citrate synthase; KEGG: met:M446_0646 citrate synthase I; Belongs to the citrate synthase family.
  
 0.879
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.878
Mnod_4814
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: met:M446_2631 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.865
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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