STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_0916Hypothetical protein; KEGG: vha:VIBHAR_06869 RNA-directed DNA polymerase. (426 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
 
 0.745
Mnod_5408
TIGRFAM: CRISPR-associated protein Cas2; KEGG: rru:Rru_A0168 hypothetical protein.
   
 
 0.745
Mnod_0915
PFAM: regulatory protein MerR; KEGG: mgi:Mflv_2925 hypothetical protein.
       0.675
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.516
Mnod_0914
KEGG: mag:amb1693 hypothetical protein.
       0.492
Mnod_3053
Serine/threonine protein kinase; PFAM: protein of unknown function RIO1; tyrosine protein kinase; protein of unknown function DUF323; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: met:M446_0913 serine/threonine protein kinase.
  
  
 0.445
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.445
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.444
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
  
 0.430
Mnod_0878
PFAM: DNA methylase N-4/N-6 domain protein; ParB domain protein nuclease; KEGG: mex:Mext_0806 DNA methylase N-4/N-6 domain-containing protein; Belongs to the N(4)/N(6)-methyltransferase family.
  
  
 0.423
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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