Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Mnod_0998PFAM: import inner membrane translocase subunit Tim44; KEGG: met:M446_1374 import inner membrane translocase subunit Tim44. (241 aa)    
Predicted Functional Partners:
Mnod_1000
PFAM: Smr protein/MutS2; KEGG: met:M446_1376 Smr protein/MutS2.
 
     0.854
Mnod_0999
PFAM: MltA domain protein; 3D domain protein; KEGG: met:M446_1375 MltA domain-containing protein.
       0.829
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
 
     0.782
Mnod_6611
PFAM: protein of unknown function DUF1013; KEGG: met:M446_6075 hypothetical protein.
  
     0.767
Mnod_0697
PFAM: protein of unknown function DUF1321; KEGG: met:M446_1093 hypothetical protein.
  
     0.741
Mnod_0379
PFAM: protein of unknown function DUF1058; KEGG: met:M446_2231 hypothetical protein.
  
     0.732
Mnod_1024
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: met:M446_1406 DNA polymerase III, delta subunit.
 
     0.719
Mnod_5956
PFAM: Disulphide bond formation protein DsbB; KEGG: met:M446_5213 disulphide bond formation protein DsbB.
  
     0.718
yidC
YidC translocase/secretase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
     0.709
Mnod_1608
TIGRFAM: double-strand break repair protein AddB; KEGG: met:M446_0491 double-strand break repair protein AddB.
  
     0.707
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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