Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1005PFAM: protein of unknown function DUF58; KEGG: met:M446_1384 hypothetical protein. (322 aa)    
Predicted Functional Partners:
Mnod_1008
SMART: von Willebrand factor type A; KEGG: met:M446_1387 von Willebrand factor type A.
 
  
 0.978
Mnod_1009
KEGG: met:M446_1388 TPR repeat-containing protein.
 
  
 0.978
Mnod_1007
PFAM: von Willebrand factor type A; KEGG: met:M446_1386 von Willebrand factor type A.
 
  
 0.971
Mnod_1010
KEGG: met:M446_1389 hypothetical protein.
 
  
 0.963
Mnod_1004
PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: met:M446_1383 ATPase.
 
  
 0.949
Mnod_1006
KEGG: met:M446_1385 hypothetical protein.
  
  
 0.872
Mnod_5171
PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: met:M446_4480 ATPase.
 
  
 0.714
Mnod_5315
KEGG: met:M446_5011 hypothetical protein.
  
     0.523
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
     
 0.485
Mnod_5323
KEGG: met:M446_5019 putative signal peptide.
 
     0.458
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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