Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_1009KEGG: met:M446_1388 TPR repeat-containing protein. (301 aa)    
Predicted Functional Partners:
Mnod_1005
PFAM: protein of unknown function DUF58; KEGG: met:M446_1384 hypothetical protein.
 
  
 0.978
Mnod_1007
PFAM: von Willebrand factor type A; KEGG: met:M446_1386 von Willebrand factor type A.
 
   
 0.965
Mnod_1008
SMART: von Willebrand factor type A; KEGG: met:M446_1387 von Willebrand factor type A.
 
     0.965
Mnod_1010
KEGG: met:M446_1389 hypothetical protein.
 
 
 0.958
Mnod_1004
PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: met:M446_1383 ATPase.
 
     0.857
Mnod_1006
KEGG: met:M446_1385 hypothetical protein.
       0.853
Mnod_5987
KEGG: met:M446_5769 hypothetical protein.
  
     0.574
Mnod_5315
KEGG: met:M446_5011 hypothetical protein.
  
     0.532
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.505
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.486
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (34%) [HD]