STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (554 aa)    
Predicted Functional Partners:
hutH
TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; KEGG: met:M446_1653 histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
 0.999
hutI
TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: met:M446_1654 imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.998
Mnod_1037
PFAM: N-formylglutamate amidohydrolase; KEGG: met:M446_1652 N-formylglutamate amidohydrolase.
 
  
 0.957
Mnod_1040
Transcriptional regulator, histidine utilization repressor, GntR family; TIGRFAM: histidine utilization repressor; formiminoglutamate deiminase; PFAM: regulatory protein GntR HTH; amidohydrolase; UbiC transcription regulator-associated domain protein; KEGG: met:M446_1655 formiminoglutamate deiminase.
 
  
 0.866
Mnod_1549
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: met:M446_4676 amidohydrolase.
  
  
 0.803
Mnod_3965
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: met:M446_3838 amidohydrolase.
  
  
 0.803
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.754
Mnod_0756
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: dac:Daci_1440 GntR family transcriptional regulator.
 
  
 0.580
Mnod_5950
PFAM: N-formylglutamate amidohydrolase; KEGG: met:M446_5219 N-formylglutamate amidohydrolase.
  
  
 0.570
Mnod_7678
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: met:M446_6964 agmatinase; Belongs to the arginase family.
  
  
 0.560
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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