Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1040Transcriptional regulator, histidine utilization repressor, GntR family; TIGRFAM: histidine utilization repressor; formiminoglutamate deiminase; PFAM: regulatory protein GntR HTH; amidohydrolase; UbiC transcription regulator-associated domain protein; KEGG: met:M446_1655 formiminoglutamate deiminase. (686 aa)    
Predicted Functional Partners:
hutI
TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: met:M446_1654 imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.989
Mnod_1037
PFAM: N-formylglutamate amidohydrolase; KEGG: met:M446_1652 N-formylglutamate amidohydrolase.
 
 
 0.984
hutH
TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; KEGG: met:M446_1653 histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
  
 0.905
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.866
Mnod_0750
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: mrd:Mrad2831_3644 AraC family transcriptional regulator.
 
  
 0.571
Mnod_1600
TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: met:M446_0494 N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.551
Mnod_2728
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: met:M446_6221 AraC family transcriptional regulator.
  
  
 0.486
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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