Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Mnod_1041KEGG: met:M446_1658 hypothetical protein. (368 aa)    
Predicted Functional Partners:
Mnod_1042
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: met:M446_1659 histidine kinase.
     
 0.729
Mnod_4967
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; CI repressor; Cupin 2 conserved barrel domain protein; KEGG: met:M446_4938 XRE family transcriptional regulator.
  
     0.509
Mnod_2705
PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: mrd:Mrad2831_0112 hypothetical protein.
  
     0.475
Mnod_1343
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: met:M446_0900 endonuclease/exonuclease/phosphatase.
  
  
 0.467
Mnod_7582
KEGG: met:M446_6846 hypothetical protein.
 
     0.459
Mnod_0713
PFAM: Peptidoglycan-binding domain 1 protein; KEGG: met:M446_1122 peptidoglycan binding domain-containing protein.
  
     0.451
Mnod_0715
KEGG: met:M446_1120 hypothetical protein.
  
     0.443
Mnod_6363
PFAM: AsmA family protein; KEGG: met:M446_5855 AsmA family protein.
 
     0.416
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
     0.414
Mnod_0718
KEGG: met:M446_1117 hypothetical protein.
  
     0.411
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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