Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1080Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: met:M446_2105 pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (247 aa)    
Predicted Functional Partners:
Mnod_1081
PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: met:M446_2106 methyltransferase small; Belongs to the methyltransferase superfamily.
 
  
 0.963
der
Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.797
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: met:M446_6548 cytidylate kinase.
  
  
 0.784
Mnod_2893
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: met:M446_4910 exodeoxyribonuclease III Xth.
  
    0.739
Mnod_3266
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: met:M446_2700 exodeoxyribonuclease III Xth.
  
    0.739
Mnod_2182
Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.717
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
   0.528
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: met:M446_5318 phenylalanyl-tRNA synthetase, beta subunit.
     
 0.521
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
    0.518
Mnod_1082
KEGG: met:M446_3447 hypothetical protein.
       0.516
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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