Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1111PFAM: amidohydrolase; Amidohydrolase 3; KEGG: met:M446_2144 amidohydrolase. (458 aa)    
Predicted Functional Partners:
Mnod_5814
TIGRFAM: hydroxyisourate hydrolase; OHCU decarboxylase; PFAM: Transthyretin; KEGG: met:M446_5250 OHCU decarboxylase.
 
  
 0.687
Mnod_4657
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: met:M446_4793 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
 
  
 0.659
Mnod_5365
TIGRFAM: OHCU decarboxylase; urate catabolism protein; PFAM: polysaccharide deacetylase; KEGG: met:M446_5068 urate catabolism protein.
 
   
 0.580
Mnod_1247
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: met:M446_1983 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
 
  
 0.504
Mnod_1011
PFAM: beta-lactamase; KEGG: met:M446_1390 beta-lactamase.
 
    0.491
Mnod_1110
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: met:M446_2139 two component LuxR family transcriptional regulator.
       0.485
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.438
Mnod_4658
PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: met:M446_4792 molybdopterin dehydrogenase FAD-binding.
 
    0.432
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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