Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1122PFAM: regulatory protein TetR; KEGG: met:M446_2160 TetR family transcriptional regulator. (242 aa)    
Predicted Functional Partners:
Mnod_7181
KEGG: met:M446_6312 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein.
  
     0.648
Mnod_0393
KEGG: met:M446_2218 hypothetical protein.
  
     0.588
Mnod_0715
KEGG: met:M446_1120 hypothetical protein.
  
     0.576
Mnod_4667
PFAM: O-antigen polymerase; KEGG: met:M446_4779 O-antigen polymerase.
  
     0.576
Mnod_2172
KEGG: met:M446_2469 hypothetical protein.
  
     0.550
Mnod_1479
Porin; Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
  
  
 0.547
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
     
 0.545
Mnod_4174
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: met:M446_4439 peptidase S1 and S6 chymotrypsin/Hap.
  
     0.542
Mnod_1311
Porin; Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
  
  
 0.530
Mnod_6363
PFAM: AsmA family protein; KEGG: met:M446_5855 AsmA family protein.
  
     0.530
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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