Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (231 aa)    
Predicted Functional Partners:
Mnod_1153
KEGG: met:M446_2194 hypothetical protein.
 
 
 0.997
Mnod_4732
PFAM: Peptidase M23; KEGG: met:M446_4222 peptidase M23B.
 
 
 
 0.883
Mnod_3755
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; KEGG: met:M446_6211 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor.
  
  
 0.759
Mnod_2229
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sus:Acid_1126 ABC transporter related.
 
     0.753
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
  
 0.733
Mnod_1155
TIGRFAM: MJ0042 family finger-like protein; KEGG: met:M446_2196 zinc finger-domain-containing protein.
       0.718
Mnod_1156
TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: met:M446_2197 hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.710
Mnod_2181
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
  
 0.679
Mnod_1152
PFAM: protein of unknown function DUF218; KEGG: met:M446_2193 hypothetical protein.
 
     0.658
rpsK
Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
     0.635
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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