Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1226KEGG: met:M446_1126 selenium-binding protein, putative. (440 aa)    
Predicted Functional Partners:
Mnod_1225
PFAM: electron transport protein SCO1/SenC; KEGG: met:M446_1125 electron transport protein SCO1/SenC.
 
     0.925
Mnod_4566
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Flavocytochrome c sulphide dehydrogenase flavin-binding; KEGG: met:M446_3049 flavocytochrome c sulphide dehydrogenase flavin-binding.
  
 
 0.922
Mnod_1031
PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: met:M446_1414 cystathionine gamma-synthase.
   
 
  0.903
Mnod_3067
TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: met:M446_3453 O-succinylhomoserine (thiol)-lyase.
   
 
  0.903
Mnod_4567
PFAM: cytochrome c class I; KEGG: met:M446_3048 cytochrome c553.
  
 
 0.903
Mnod_3098
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: met:M446_1598 oxidoreductase FAD/NAD(P)-binding subunit.
    
  0.902
Mnod_5015
KEGG: bja:blr1218 hypothetical protein.
    
  0.901
Mnod_1803
Flavodoxin/nitric oxide synthase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
     
  0.900
cysI
Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
  0.900
Mnod_2756
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpt:Rpal_2837 pyridoxal-5'-phosphate-dependent protein beta subunit.
     
  0.900
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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