Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_1375PFAM: protein of unknown function DUF526; KEGG: met:M446_0853 hypothetical protein. (96 aa)    
Predicted Functional Partners:
Mnod_1376
PFAM: Protein of unknown function DUF1790; KEGG: met:M446_0854 hypothetical protein.
 
     0.736
Mnod_5287
KEGG: met:M446_3096 hypothetical protein.
  
     0.682
Mnod_4791
PFAM: conserved hypothetical protein; KEGG: met:M446_2637 hypothetical protein; Belongs to the UPF0262 family.
  
     0.671
Mnod_4427
PFAM: UspA domain protein; KEGG: met:M446_3395 UspA domain-containing protein.
  
     0.647
Mnod_1373
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_0851 integral membrane sensor signal transduction histidine kinase.
       0.571
Mnod_1374
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: met:M446_0852 two component transcriptional regulator.
       0.549
Mnod_6738
KEGG: met:M446_6497 cobalt chelatase, pCobT subunit; TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase CobT subunit; SMART: von Willebrand factor type A.
  
     0.504
Mnod_6068
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: met:M446_5115 integral membrane sensor signal transduction histidine kinase.
  
     0.475
Mnod_7066
PFAM: protein of unknown function DUF1476; KEGG: met:M446_6239 hypothetical protein.
  
     0.471
atpF-2
H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
  
     0.467
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.