Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_1389KEGG: met:M446_0863 hypothetical protein. (89 aa)    
Predicted Functional Partners:
Mnod_2128
TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: mrd:Mrad2831_2592 nitrate reductase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.934
Mnod_2127
TIGRFAM: nitrate reductase, beta subunit; KEGG: mrd:Mrad2831_2591 nitrate reductase, beta subunit.
  
 
 0.895
Mnod_1390
SMART: WD-40 repeat protein; KEGG: met:M446_0862 WD-40 repeat-containing protein.
       0.853
Mnod_2125
TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit; KEGG: mrd:Mrad2831_2589 respiratory nitrate reductase, gamma subunit.
  
  
 0.810
Mnod_2864
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
    0.780
Mnod_1700
PFAM: major facilitator superfamily MFS_1; KEGG: met:M446_4825 major facilitator transporter.
  
  
 0.524
Mnod_2131
PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_2594 major facilitator transporter.
  
  
 0.524
Mnod_2422
PFAM: major facilitator superfamily MFS_1; KEGG: xau:Xaut_2926 major facilitator transporter.
  
  
 0.524
Mnod_1391
PFAM: response regulator receiver; KEGG: met:M446_0861 response regulator receiver protein.
       0.487
Mnod_1170
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: met:M446_1812 glutamate synthase (ferredoxin).
      
 0.428
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: medium (48%) [HD]