Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1458PFAM: FAD linked oxidase domain protein; KEGG: rru:Rru_A1124 D-lactate dehydrogenase (cytochrome). (478 aa)    
Predicted Functional Partners:
Mnod_7392
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: met:M446_6648 FMN-dependent alpha-hydroxy acid dehydrogenase.
  
 0.939
Mnod_2174
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_2472 malate dehydrogenase.
  
 
 0.920
Mnod_2328
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_1243 malate dehydrogenase.
  
 
 0.920
Mnod_7102
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_6546 malate dehydrogenase.
  
 
 0.920
pdhA-2
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.911
Mnod_6516
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.911
Mnod_0414
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: met:M446_2089 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family.
  
 0.910
Mnod_2849
TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: met:M446_2710 pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.910
dld
D-lactate dehydrogenase membrane binding; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
     
 0.910
Mnod_0655
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: met:M446_6782 pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.909
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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