Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpsUPFAM: ribosomal protein S21; KEGG: met:M446_0684 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (96 aa)    
Predicted Functional Partners:
rpsP
PFAM: ribosomal protein S16; KEGG: met:M446_3682 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.989
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
 
 0.988
rpmB
PFAM: ribosomal protein L28; KEGG: met:M446_3667 ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.987
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.986
rpsO
Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
 
 0.985
rpsB
PFAM: ribosomal protein S2; KEGG: met:M446_4827 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.983
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.983
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 
 0.983
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.982
rpmI
PFAM: ribosomal protein L35; KEGG: met:M446_5321 ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
  
 
 0.982
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (26%) [HD]