Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1540KEGG: met:M446_0629 putative mRNA 3-end processing factor. (345 aa)    
Predicted Functional Partners:
Mnod_1541
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: met:M446_0628 ATP dependent DNA ligase.
 0.990
Mnod_5293
PFAM: WD-40 repeat protein; cytochrome c class I; KEGG: met:M446_3100 cytochrome c class I.
  
 0.891
Mnod_0010
PFAM: protein of unknown function DUF29; KEGG: mrd:Mrad2831_1125 hypothetical protein.
   
 0.879
Mnod_1390
SMART: WD-40 repeat protein; KEGG: met:M446_0862 WD-40 repeat-containing protein.
    
 0.866
Mnod_1542
PFAM: protein of unknown function UPF0047; KEGG: met:M446_0627 hypothetical protein.
       0.853
Mnod_4760
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases; KEGG: met:M446_4251 DEAD/DEAH box helicase domain-containing protein.
 
    0.840
Mnod_4759
KEGG: met:M446_4250 putative ICC-like phosphoesterase.
 
     0.833
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.803
Mnod_7211
KEGG: met:M446_6289 hypothetical protein.
  
 0.758
Mnod_1539
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: met:M446_0630 methyltransferase type 12.
       0.737
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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