Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1710PFAM: Methyltransferase type 11; KEGG: met:M446_4813 methyltransferase type 11. (295 aa)    
Predicted Functional Partners:
Mnod_1711
PFAM: protein of unknown function DUF427; KEGG: met:M446_4812 hypothetical protein.
       0.853
Mnod_1655
PFAM: ETC complex I subunit conserved region; KEGG: met:M446_0438 ETC complex I subunit region.
  
     0.750
Mnod_5254
PFAM: protein of unknown function DUF185; KEGG: met:M446_3290 hypothetical protein.
  
     0.740
Mnod_4132
NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
  
   
 0.667
Mnod_0369
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: met:M446_2240 NADH dehydrogenase (ubiquinone).
 
     0.661
Mnod_1709
KEGG: rpe:RPE_4243 hypothetical protein.
     
 0.655
Mnod_1708
KEGG: met:M446_4814 phosphoribosyltransferase.
       0.582
Mnod_0513
PFAM: cytochrome c class I; KEGG: met:M446_1618 cytochrome c class I.
  
    0.569
Mnod_7121
PFAM: ATP12 ATPase; KEGG: met:M446_6370 ATP12 ATPase.
  
     0.566
Mnod_4583
PFAM: cytochrome c class I; KEGG: met:M446_3032 cytochrome c class I.
  
    0.560
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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