Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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cysISulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (602 aa)    
Predicted Functional Partners:
Mnod_1803
Flavodoxin/nitric oxide synthase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
 
 0.998
Mnod_2866
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; Fe-S cluster domain protein; KEGG: met:M446_3748 oxidoreductase FAD/NAD(P)-binding subunit.
 
 0.996
Mnod_1801
Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite.
 
 0.990
Mnod_3098
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: met:M446_1598 oxidoreductase FAD/NAD(P)-binding subunit.
 
 0.987
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
  
 0.974
Mnod_2864
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.961
Mnod_2756
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpt:Rpal_2837 pyridoxal-5'-phosphate-dependent protein beta subunit.
  
 
 0.943
Mnod_5186
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: met:M446_4466 cysteine synthase A.
  
 
 0.943
Mnod_2710
PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mpt:Mpe_A0921 methanesulfonate monooxygenase component; reductase.
   
 0.925
Mnod_6380
PFAM: Rhodanese domain protein; KEGG: met:M446_5874 rhodanese domain-containing protein.
    
 0.924
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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