Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_1887PFAM: Glutathione S-transferase domain; KEGG: met:M446_0376 glutathione S-transferase domain-containing protein; Belongs to the GST superfamily. (206 aa)    
Predicted Functional Partners:
Mnod_4666
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
  
 0.932
gshB
TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; KEGG: met:M446_1113 glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
 
  
 0.926
Mnod_6935
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
  
 
 0.926
Mnod_1885
PFAM: tRNA synthetase class II (D K and N); KEGG: met:M446_0378 lysine--tRNA ligase.
       0.853
Mnod_1886
TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: met:M446_0377 lysine 2,3-aminomutase YodO family protein.
       0.853
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
  
 0.736
Mnod_6012
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
  0.721
Mnod_4445
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
  0.703
Mnod_1782
PFAM: glutathione peroxidase; KEGG: met:M446_5475 glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 
 0.700
Mnod_5332
PFAM: glutathione peroxidase; KEGG: met:M446_5025 peroxiredoxin; Belongs to the glutathione peroxidase family.
   
 
 0.700
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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