Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_2078PFAM: protein of unknown function DUF465; KEGG: met:M446_2691 hypothetical protein. (75 aa)    
Predicted Functional Partners:
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.728
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.728
Mnod_0693
KEGG: met:M446_1097 hypothetical protein.
  
     0.471
Mnod_2079
PFAM: protein of unknown function DUF465; KEGG: met:M446_2690 hypothetical protein.
       0.457
Mnod_2075
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: met:M446_2695 TPR repeat-containing protein.
       0.445
rpmJ
TIGRFAM: ribosomal protein L36; KEGG: met:M446_5210 ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
 
     0.416
bpt
Arginine-tRNA-protein transferase domain protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.
  
     0.411
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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