Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Mnod_2152TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: met:M446_2441 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (263 aa)    
Predicted Functional Partners:
Mnod_2153
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: met:M446_2442 precorrin-3B C17-methyltransferase.
 
 0.999
Mnod_2151
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: met:M446_2440 precorrin-8X methylmutase.
 
  
 0.996
Mnod_2150
PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: met:M446_2439 nitrite/sulfite reductase hemoprotein beta subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.995
Mnod_2157
TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: met:M446_2446 precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.983
Mnod_2154
TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: met:M446_2443 precorrin-6x reductase.
 
  
 0.981
Mnod_2155
TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: met:M446_2444 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.
 
  
 0.978
Mnod_2864
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
 
 0.976
Mnod_2149
TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase; KEGG: met:M446_2438 cobaltochelatase, CobN subunit.
 
  
 0.975
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.969
Mnod_2156
KEGG: met:M446_2445 cobalamin (vitamin B12) biosynthesis CbiG protein.
 
  
 0.946
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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