Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_2160PFAM: helix-turn-helix domain protein; KEGG: met:M446_2456 XRE family transcriptional regulator. (134 aa)    
Predicted Functional Partners:
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.748
Mnod_6611
PFAM: protein of unknown function DUF1013; KEGG: met:M446_6075 hypothetical protein.
  
     0.709
Mnod_7273
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_6014 integral membrane sensor signal transduction histidine kinase.
  
     0.633
Mnod_3489
TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; KEGG: ccr:CC_0705 hypothetical protein.
  
     0.625
Mnod_2963
KEGG: met:M446_1049 hypothetical protein.
  
     0.620
Mnod_0447
PFAM: Methyltransferase type 11; KEGG: met:M446_2064 methyltransferase type 11.
  
     0.614
Mnod_6972
Putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; KEGG: gox:GOX1693 cell cycle transcriptional regulator CtrA.
  
     0.609
Mnod_5564
PFAM: DNA polymerase III chi subunit HolC; KEGG: met:M446_5406 DNA polymerase III chi subunit HolC.
  
     0.596
Mnod_1024
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: met:M446_1406 DNA polymerase III, delta subunit.
  
     0.588
Mnod_5169
TIGRFAM: conserved hypothetical membrane protein; KEGG: met:M446_4482 hypothetical protein.
  
     0.588
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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