Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_2177TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: met:M446_2479 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (296 aa)    
Predicted Functional Partners:
Mnod_2175
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: met:M446_2475 methylmalonate-semialdehyde dehydrogenase.
 
 
 0.957
Mnod_2521
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: mpo:Mpop_4215 methylmalonate-semialdehyde dehydrogenase.
 
 
 0.925
Mnod_5498
PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: azc:AZC_2905 putative 3-hydroxyisobutyrate dehydrogenase.
  
  
 
0.919
Mnod_2908
PFAM: Aldehyde Dehydrogenase; KEGG: rec:RHECIAT_PC0000542 putative aldehyde dehydrogenase (NAD(+)) protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.912
Mnod_5499
PFAM: Aldehyde Dehydrogenase; KEGG: bbt:BBta_5124 putative aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.912
Mnod_2525
TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ret:RHE_PE00281 putative 3-hydroxyisobutyrate dehydrogenase protein; Belongs to the HIBADH-related family.
  
  
 
0.902
Mnod_3410
PFAM: aminotransferase class-III; KEGG: met:M446_0765 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
Mnod_4458
PFAM: aminotransferase class-III; KEGG: met:M446_3237 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
Mnod_7569
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: met:M446_6833 enoyl-CoA hydratase/isomerase.
  
 0.871
Mnod_1878
Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: met:M446_0385 carbamoyl-phosphate synthase L chain ATP-binding.
  
 
 0.837
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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