Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
Mnod_2190PFAM: protein of unknown function DUF498; KEGG: met:M446_2493 hypothetical protein. (129 aa)    
Predicted Functional Partners:
Mnod_2191
PFAM: Squalene/phytoene synthase; KEGG: met:M446_2494 squalene/phytoene synthase.
 
     0.932
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.853
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.735
yajC
Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
       0.615
Mnod_2186
PFAM: protein of unknown function DUF815; KEGG: met:M446_2488 hypothetical protein.
 
     0.596
Mnod_1710
PFAM: Methyltransferase type 11; KEGG: met:M446_4813 methyltransferase type 11.
  
     0.538
Mnod_0369
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: met:M446_2240 NADH dehydrogenase (ubiquinone).
  
     0.491
Mnod_7121
PFAM: ATP12 ATPase; KEGG: met:M446_6370 ATP12 ATPase.
 
     0.490
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: met:M446_2230 ferric uptake regulator family protein; Belongs to the Fur family.
  
     0.425
Mnod_3715
TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: met:M446_2654 molybdopterin converting factor, subunit 1.
 
     0.403
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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