Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_2235PFAM: protein of unknown function LppY and LpqO; KEGG: met:M446_6160 protein of unknown function LppY and LpqO. (320 aa)    
Predicted Functional Partners:
Mnod_2231
KEGG: met:M446_6157 hypothetical protein.
 
     0.726
Mnod_2238
SMART: Rhodanese domain protein; KEGG: met:M446_6163 rhodanese domain-containing protein.
  
    0.722
Mnod_2236
KEGG: met:M446_6161 hypothetical protein.
       0.675
Mnod_2237
TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: met:M446_6162 chromate transporter.
       0.670
Mnod_2234
PFAM: manganese and iron superoxide dismutase; KEGG: met:M446_6159 manganese and iron superoxide dismutase.
 
   
 0.624
cobB-2
PFAM: Silent information regulator protein Sir2; KEGG: met:M446_5854 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
   
    0.585
Mnod_6353
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_5171 GAF sensor hybrid histidine kinase.
 
  
 0.541
Mnod_5657
KEGG: met:M446_1942 tetratricopeptide TPR_4.
  
     0.481
Mnod_2227
KEGG: bvi:Bcep1808_7486 hypothetical protein.
 
     0.443
Mnod_2239
PFAM: conserved hypothetical protein; KEGG: met:M446_0072 hypothetical protein.
       0.414
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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