Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_2253PFAM: NHL repeat containing protein; SMP-30/Gluconolaconase/LRE domain protein; KEGG: sen:SACE_3449 gluconolactonase precursor. (307 aa)    
Predicted Functional Partners:
Mnod_0981
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: reh:H16_A1934 threonine dehydrogenase (Zn dependent).
  
 
  0.813
Mnod_2254
KEGG: rfr:Rfer_2748 extracellular solute-binding protein.
       0.668
Mnod_2255
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsh:Rsph17029_4152 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.500
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
  
 0.487
Mnod_2256
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbr:BB1018 transmembrane permease ABC transporter protein.
       0.476
Mnod_2257
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: reh:H16_A2382 ABC-type transporter, ATPase component: NitT family.
       0.476
Mnod_2258
NMT1/THI5 like domain protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; NMT1/THI5 like domain protein; SMART: extracellular solute-binding protein family 3; KEGG: rso:RSc1198 signal peptide protein.
       0.476
Mnod_6088
PFAM: beta-lactamase; KEGG: met:M446_5348 beta-lactamase.
 
     0.460
Mnod_3006
PFAM: beta-lactamase; KEGG: met:M446_2694 beta-lactamase.
 
     0.417
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
  
 0.414
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.